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March 1981

Raised Plasma Urea Levels After Myocardial Infarction

Author Affiliations

From the Department of Clinical Chemistry, General Hospital, Burton-on-Trent, England (Dr Moseley); and Department of Chemical Pathology, The General Infirmary, Leeds, England (Drs Swaminathan and Morgan).

Arch Intern Med. 1981;141(4):438-440. doi:10.1001/archinte.1981.00340040034013

• Plasma and urine urea and creatinine levels were measured in 50 consecutive patients admitted to a coronary care unit. Forty of the patients had had myocardial infarction; their average plasma urea level increased substantially by the third day after admission, when 50% of the patients had an "abnormally" high plasma urea level. There was no change in plasma urea levels in ten patients who had not had a myocardial infarction. Results indicate that a rise in plasma urea level is common if not universal after myocardial infarction and is caused by either a fall in the glomerular filtration rate or an increased urea production rather than a mixture of the two.

(Arch Intern Med 1981;141:438-440)