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April 1981

An Audit of Chloramphenicol Use in a Large Community Hospital

Author Affiliations

From the Department of Family Medicine, University of Connecticut Health Center, Farmington (Drs Feder and Osier), and the Department of Pediatrics (Dr Feder) and the Medical Research Laboratory and Infectious Disease Division, Department of Medicine (Dr Maderazo), Hartford (Conn) Hospital.

Arch Intern Med. 1981;141(5):597-598. doi:10.1001/archinte.1981.00340050049013

• In a large community hospital during a six-month period, 238 of 19,670 hospitalized patients (1.2%) received chloramphenicol. The drug was administered exclusively by the intravenous route in 98% of these patients. In 78% of the patients, chloramphenicol was used for an appropriate indication, whereas in 22% its use was inappropriate. Serious toxic effects and unexpected clinical failures were not observed.

(Arch Intern Med 1981;141:597-598)