• In a large community hospital during a six-month period, 238 of 19,670 hospitalized patients (1.2%) received chloramphenicol. The drug was administered exclusively by the intravenous route in 98% of these patients. In 78% of the patients, chloramphenicol was used for an appropriate indication, whereas in 22% its use was inappropriate. Serious toxic effects and unexpected clinical failures were not observed.
(Arch Intern Med 1981;141:597-598)
Feder HM, Osier C, Maderazo EG. An Audit of Chloramphenicol Use in a Large Community Hospital. Arch Intern Med. 1981;141(5):597-598. doi:10.1001/archinte.1981.00340050049013