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April 1981

Nephrotic Syndrome, Linear Glomerular IgG Deposits, and Minimal Glomerular ChangesReport of a Case

Author Affiliations

From the Hôpital Broussais (Drs Jacquot, Nochy, Bariety, and Druet) and Centre Departemental de Transfusion du Val-de-Marne, Hôpital Henri Mondor (Dr Radeau), Paris.

Arch Intern Med. 1981;141(5):670-672. doi:10.1001/archinte.1981.00340050116028

• A young adult patient had an unusual acute idiopathic nephrotic syndrome. This nephrotic syndrome was remarkable for (1) association with acute renal failure and hypertension, (2) finding of minimal glomerular changes with a linear fixation of the anti-human IgG conjugate along the glomerular capillary wall without demonstrable antiglomerular basement membrane antibodies, and (3) complete recovery, including disappearance of the linear staining, after treatment with prednisone, cyclophosphamide, and plasmapheresis.

(Arch Intern Med 1981;141:670-672)