[Skip to Content]
[Skip to Content Landing]
April 1981

Hypocalcemia Associated With a Calcitonin-Producing Hepatocellular Carcinoma

Author Affiliations

From the Division of Medical Oncology, Georgetown University Medical School, Washington, DC (Dr Maguire), and the Cancer Therapy Evaluation Program, Division of Cancer Treatment, National Cancer Institute, Bethesda, Md (Dr Macdonald).

Arch Intern Med. 1981;141(5):687-688. doi:10.1001/archinte.1981.00340050133032

• We report a case of symptomatic hypocalcemia with a calcitonin-producing tumor. This case is unusual for two reasons. First, the primary tumor was a hepatocellular carcinoma that was producing large amounts of calcitonin. To our knowledge, well-defined cases of calcitonin-secreting hepatoma have not been previously reported. Second, the patient's hypercalcemia was shown to be secondary to hypomagnesemic inhibition of parathyroid function and not related to hypercalcitonemia.

(Arch Intern Med 1981;141:687-688)