May 1981

Diabetic Nephropathy in a Patient With Maturity-Onset Diabetes of the Young

Author Affiliations

From the Department of Medicine, Montefiore Hospital and University of Pittsburgh School of Medicine.

Arch Intern Med. 1981;141(6):791-792. doi:10.1001/archinte.1981.00340060099022

• A 27-year-old woman with maturity-onset diabetes of the young had a nephrotic syndrome and congestive heart failure. Studies disclosed severe diabetic retinopathy and nephropathy. The patient's HLA type at the A and B loci did not contain markers previously associated with diabetic vascular disease. To our knowledge, this is the first patient with maturity-onset diabetes of the young to be described with serious vascular disease and absence of previously described HLA markers for microangiopathy.

(Arch Intern Med 1981;141:791-792)