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May 1981

Response to Megestrol in Male Breast Carcinoma

Author Affiliations

From the Department of Internal Medicine (Dr Mitsuyasu) and Section of Medical Oncology (Drs Bonomi and Anderson), Rush Medical Center, Chicago; and the Department of Radiation Therapy, Hinsdale Hospital, Hinsdale, Ill (Dr Fischer).

Arch Intern Med. 1981;141(6):809-810. doi:10.1001/archinte.1981.00340060117031

• Sequential ablative hormonal manipulations have produced tumor regressions in metastatic male breast carcinoma. Information with regard to the use of additive hormonal therapy after orchiectomy is limited. Regression of a pulmonary metastasis during treatment with megestrol acetate occurred in a man who had metastatic steroid receptor-positive breast carcinoma that had progressed after orchiectomy.

(Arch Intern Med 1981;141:809-810)