• A 63-year-old woman with Crohn's ileocolitis, complicated by ileal adenocarcinoma two years previously, was admitted for examination of weight loss and fatigue. Colonoscopy demonstrated an area of flat, ulcerated mucosa in the sigmoid colon that proved to be an adenocarcinoma in an area of Crohn's colitis; a sigmoid resection and primary anastomosis were performed. Metachronous carcinoma of the large and small bowel occurred in areas involved with Crohn's disease.
(Arch Intern Med 1981;141:1074-1075)
Castellano TJ, Frank MS, Brandt LJ, Mahadevia P. Metachronous Carcinoma Complicating Crohn's Disease. Arch Intern Med. 1981;141(8):1074-1075. doi:10.1001/archinte.1981.00340080110023