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July 1981

Beneficial Effect of Hepatitis in Leukemic Reticuloendotheliosis

Author Affiliations

From the Departments of Medicine (Drs Brody, Krantz, and Graber) and Pathology (Dr Russell), Veterans Administration Medical Center and Vanderbilt University School of Medicine, Nashville, Tenn.

Arch Intern Med. 1981;141(8):1080-1081. doi:10.1001/archinte.1981.00340080116026

• A patient with leukemic reticuloendotheliosis had splenomegaly, neutropenia, and a severe underproduction anemia. During a three-year period, the hematocrit was never in the normal range, and periodic transfusions were required. However, after an episode of hepatitis that was positive for B surface antigen, the spleen became smaller, the number of neutrophils increased, the transfusion requirement disappeared, and the hematocrit rose to normal. Several mechanisms for this observation are proposed.

(Arch Intern Med 1981;141:1080-1081)