September 1981

Angioimmunoblastic Lymphadenopathy, Bence Jones Proteinuria, and Acute Renal Failure

Author Affiliations

From the Departments of Medicine (Drs Bhat, Kerpen, Murthy, and Horowitz) and Pathology (Dr Valderrama), Queens Hospital Center and Long Island Jewish-Hillside Medical Center Affiliation, Jamaica, NY, and the Health Sciences Center, State University of New York at Stony Brook (Drs Bhat, Kerpen, and Valderrama).

Arch Intern Med. 1981;141(10):1373-1374. doi:10.1001/archinte.1981.00340100129028

Acute renal failure developed in a 77-year-old woman with angioimmunoblastic lymphadenopathy (AIL) with Bence Jones proteinuria. Percutaneous renal biopsy and autopsy revealed obliteration of tubules by eosinophilic proteinaceous casts, some of which were surrounded by multinucleated giant cells. Bence Jones proteinuria has already been described as a part of dysproteinemia in AIL. We believe this to be the first reported case of AIL with Bence Jones proteinuria and acute renal failure due to "myeloma-like kidney."

(Arch Intern Med 1981;141:1373-1374)