Reports of cutaneous manifestations of hypersensitivity to the vasodilator minoxidil have described only minor eruptions. A fulminant example of the Stevens-Johnson syndrome developed in a patient during minoxidil therapy, disappeared with cessation of administration of the drug, and recrudesced on reexposure to the drug.
(Arch Intern Med 1981;141:1515)
DiSantis DJ, Flanagan J. Minoxidil-Induced Stevens-Johnson Syndrome. Arch Intern Med. 1981;141(11):1515. doi:10.1001/archinte.1981.00340120123025