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November 1981

Invasive Amebiasis

Arch Intern Med. 1981;141(12):1724. doi:10.1001/archinte.1981.00340130162047

To the Editor.  —The case report by Kovaleski et al entitled "Treatment of an Amebic Liver Abscess With Intravenous Metronidazole," published in the Archives (1981;141:132-134), and accompanying editorial (p 20) pointed out the great advance provided by serologic tests in the diagnosis of invasive amebiasis. I saw a case in which these tests would have been extremely valuable.

Report of a Case.  —A 69-year-old man, a native of British Guyana, was seen initially with a history of fever and right upper quadrant pain. Sonogram and technetium Tc 99m sulfur colloid liver scan showed a 12-cm cystic area in the right lobe of the liver. The patient was treated with clindamycin phosphate, ampicillin sodium, and gentamicin sulfate for a presumed pyogenic liver abscess. A serum specimen was sent to the Centers for Disease Control (CDC), Atlanta, for amebic serologic study. After two weeks of therapy, the patient's condition had not improved,

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