[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.166.80.147. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
January 1982

Erroneous C-Peptide Values Given?-Reply

Author Affiliations

Charleston, SC

Boston

Arch Intern Med. 1982;142(1):201. doi:10.1001/archinte.1982.00340140203043
Abstract

—Thank you for your comments on C-peptide methodology, which are quite correct, regarding interference from insulin antibodies. The levels reported in the letter we published were obtained before precipitation of antibodies (nonpolyethylene glycol [PEG] values). However, on the day after the first determination, the assay was repeated after PEG precipitation of antibodies. This produced

a normal C-peptide response to glucose, given in the Table. The method was that of Kuzuya et al.1 All values of C-peptide obtained using PEG are comparable to values obtained using the C-peptide methodology in glucose tolerance testing from normal persons.

First Page Preview View Large
First page PDF preview
First page PDF preview
×