July 1982

Alveolar Rhabdomyosarcoma Associated With Disseminated Intravascular Coagulation and a Unique Factor VIII Antigen

Author Affiliations

From the Hematology and Oncology Service, Walter Reed Army Medical Center, Washington, DC. Dr Butler is currently with the University of South Carolina School of Medicine, Columbia.

Arch Intern Med. 1982;142(7):1379-1380. doi:10.1001/archinte.1982.00340200149029

• Disseminated intravascular coagulation (DIC) has been described in association with many tumors. We describe a patient with alveolar rhabdomyosarcoma in whom DIC developed with the initiation of chemotherapy. The patient achieved complete remission of his tumor for 14 months. An unusual factor VIII antigen was identified on crossed immunoelectrophoresis that was present at initial diagnosis, disappeared with remission, and returned with relapse of the tumor.

(Arch Intern Med 1982;142:1379-1380)