July 1982

To the Editor.—-Reply

Arch Intern Med. 1982;142(7):1408. doi:10.1001/archinte.1982.00340200178041

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—Dr Silberstein points out that the low specificity of 67Ga scans that we recently reported was caused, in large part, by nonspecific accumulation of 67Ga in the GI tract. He further states that the specificity would have been improved had we obtained follow-up scans to see the radionuclide cleared from the intestine. Although we agree that specificity may have been improved had we obtained 72- and, possibly, 96-hour images, we hasten to make the following points: (1) other major medical centers are experiencing results similar to ours with 67Ga (see the accompanying letter from Drs McDougall and Goodwin), and (2) the possibility of increasing specificity of 67Ga scanning by obtaining 72- and 96-hour images is accompanied by a frequently unacceptable delay in providing meaningful results to the clinician. We, therefore, share Silberstein's as well as McDougall and Goodwin's interest in 111In—labeled oxyquinoline WBC scans in

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