October 1982

Pseudomonas Peritonitis and Continuous Ambulatory Peritoneal Dialysis

Author Affiliations

From the Renal Section, Department of Internal Medicine, Veterans Administration Medical Center and Baylor College of Medicine (Drs Krothapalli, Duffy, and Senekjian, and Ms Lacke and Mr Payne), and the Nursing Service, VA Medical Center (Mss Patel and Perez), Houston. Drs Krothapalli and Duffy are fellows in nephrology at the Baylor College of Medicine.

Arch Intern Med. 1982;142(10):1862-1863. doi:10.1001/archinte.1982.00340230108019

In a population of 44 patients receiving continuous ambulatory peritoneal dialysis (CAPD) for a total of 591 patient months, there were 104 episodes of peritonitis. The organisms were gram-positive in 65.4%, gram-negative in 23.1%, and cultures of the dlalysate were sterile in 11.5%. Pseudomonas aeruginosa was the most frequently encountered gram-negative organism, accounting for 38.5% of the gram-negative infections or 9.6% of all infections. In all cases of P aeruginosa peritonitis, aminoglycoside antibiotic therapy for up to four weeks failed to eradicate the infection, and all patients required removal of the Tenckhoff catheter because of the presence of a sinus tract infection. We conclude that P aeruginosa is the most frequent cause of gram-negative peritonitis in patients receiving CAPD. The presence of a sinus tract infection should be suspected in all patients in whom peritonitis secondary to this organism develops. Removal of the Tenckhoff catheter will be required to cure the peritoneal infection.

(Arch Intern Med 1982;142:1862-1863)