February 1983

Fatal Disseminated Cytomegalovirus Infection in an Apparently Normal Adult

Author Affiliations

From the Department of Medicine, Divisions of Hematology (Drs Rustgi, O'Brien, and Sacher) and Infectious Diseases (Dr Garagusi), and the Department of Pathology (Dr Sacher), Georgetown University School of Medicine, Washington, DC.

Arch Intern Med. 1983;143(2):372-373. doi:10.1001/archinte.1983.00350020198039

• An ostensibly normal 43-year-old man had intermittent fever, erythema multiforme, and leukopenia that evolved into fulminant hepatic and bone marrow necrosis. The cause of his illness was compatible with cytomegalovirus (CMV) infection since there was a fourfold increase in immunofluorescent antibody titer. This report suggests that CMV can produce a rapidly progressive and overwhelming infection in an apparently healthy adult.

(Arch Intern Med 1983;143:372-373)