[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
April 1983

Production of Abnormal Systolic Sounds by Vibration of Torn Leaflet of Porcine Xenograft

Author Affiliations

From the Charles A. Dana Research Institute and the Department of Medicine, Harvard-Thorndike Laboratory, Beth Israel Hospital and Harvard Medical School, Boston.

Arch Intern Med. 1983;143(4):801-803. doi:10.1001/archinte.1983.00350040191028

• A 72-year-old woman was initially seen with increasing dyspnea and a new murmur occurring six years after mitral valve replacement with a glutaraldehyde-stabilized porcine xenograft. Prominent systolic sounds, superimposed on a softer holosystolic murmur, were audible, with a frequency of 22 to 40 Hz documented by phonocardiography. The mitral valve echo showed a prominent systolic flutter with frequency characteristics identical to those of the discrete systolic sounds, indicating that fluttering of the mitral valve was responsible for the generation of the unusual auscultatory findings. A torn porcine cusp was found at operation.

(Arch Intern Med 1983;143:801-803)