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Article
April 1983

Peripheral Nerve Damage in Patients With Nontraumatic Rhabdomyolysis

Author Affiliations

From the Division of Nephrology and the Department of Medicine, University of Southern California School of Medicine, Los Angeles.

Arch Intern Med. 1983;143(4):835-837. doi:10.1001/archinte.1983.00350040225039
Abstract

• Four patients with rhabdomyolysis due to drug intoxication were found to have peripheral nerve damage. Three patients were comatose and one was lethargic. The diagnosis of rhabdomyolysis was made by marked elevation in blood levels of creatine phosphokinase and strongly positive orthotoluidine test without RBCs in the urine. Acute renal failure developed in three patients and one had mild renal insufficiency. Electromyography showed damage to the brachial plexus in three of the patients and there was involvement of the musculocutaneous, radial, ulnar, and peroneal nerves in the fourth patient. The neurologic abnormalities disappeared completely within six weeks in two patients and considerably improved within four weeks in another patient after discharge from the hospital.

(Arch Intern Med 1983;143:835-837)

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