• A previously healthy 49-year-old woman had symptoms of acute hypercalcemia that was not parathyroid-hormone mediated. Despite no clinical signs or symptoms of arthritis, a bone scan showed increased uptake in the juxtaarticular areas of the joints in the upper and lower extremities. The biopsy specimen of skeletal lesions noted on roentgenograms supported a diagnosis of multiple myeloma. Symmetrical lesions on bone scan in a patient with asymptomatic joints and acute hypercalcemia may be the first sign of an underlying hematologic malignant neoplasm.
(Arch Intern Med 1983;143:1779-1780)
Licata AA, Farnand B, Gangemi R, Breckenridge R. Symmetrical Bone Scan in a Patient With Acute Hypercalcemia. Arch Intern Med. 1983;143(9):1779-1780. doi:10.1001/archinte.1983.00350090157026