September 1983

Symmetrical Bone Scan in a Patient With Acute Hypercalcemia

Author Affiliations

From the Department of Endocrinology, The Cleveland (Ohio) Clinic (Dr Licata), and the Department of Medicine, Rochester (NY) General Hospital (Drs Farnand, Gangemi, and Breckenridge).

Arch Intern Med. 1983;143(9):1779-1780. doi:10.1001/archinte.1983.00350090157026

• A previously healthy 49-year-old woman had symptoms of acute hypercalcemia that was not parathyroid-hormone mediated. Despite no clinical signs or symptoms of arthritis, a bone scan showed increased uptake in the juxtaarticular areas of the joints in the upper and lower extremities. The biopsy specimen of skeletal lesions noted on roentgenograms supported a diagnosis of multiple myeloma. Symmetrical lesions on bone scan in a patient with asymptomatic joints and acute hypercalcemia may be the first sign of an underlying hematologic malignant neoplasm.

(Arch Intern Med 1983;143:1779-1780)