September 1983

Liver Disease in Mixed Connective Tissue Disease

Author Affiliations

From the Department of Internal Medicine, Division of Digestive Diseases and Nutrition, University of Nebraska Medical Center, Omaha (Dr Marshall); and the Department of Internal Medicine, Divisions of Gastroenterology and Liver Disease (Dr Ravendhran) and Immunology and Rheumatology (Dr Sharp), University of Missouri Health Sciences Center, Columbia.

Arch Intern Med. 1983;143(9):1817-1818. doi:10.1001/archinte.1983.00350090199039

• Previous descriptions of mixed connective tissue disease (MCTD) have not included evidence of hepatic involvement. A patient who had MCTD also had severe chronic active hepatitis. Retrospective review of all of our cases of MCTD confirms that liver disease is an uncommon occurrence in MCTD.

(Arch Intern Med 1983;143:1817-1818)