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October 1983

Blood and Extracellular Fluid Volume in Patients With Bartter's Syndrome

Author Affiliations

From the Department of Nephrology and Hypertension, University Hospital, Utrecht, the Netherlands.

Arch Intern Med. 1983;143(10):1902-1905. doi:10.1001/archinte.1983.00350100064017

• Blood and extracellular fluid volumes were measured in four adult patients with Bartter's syndrome and compared with those of 21 healthy control subjects. Extracellular fluid volumes were significantly lower than in the control group (-7%), whereas blood volumes were within the normal range. Consequently, the ratio of blood volume to interstitial fluid volume was significantly elevated (0.42 v normal 0.35). The results are consistent with the concept that a tubular reabsorption defect is present in Bartter's syndrome.

(Arch Intern Med 1983;143:1902-1905)