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October 1983

Pseudomonas stutzeri Bacteremia Associated With Hemodialysis

Author Affiliations

From the Infectious Disease Section, Department of Medicine, Veterans Administration Medical Center (Ms Goetz, Drs Yu and Hanchett, and Mr Rihs), Pittsburgh, and the University of Pittsburgh (Dr Yu).

Arch Intern Med. 1983;143(10):1909-1912. doi:10.1001/archinte.1983.00350100073018

Pseudomonas stutzeri bacteremia developed in six patients undergoing hemodialysis. Fever, shaking chills, nausea, and vomiting were observed. All patients recovered, although only two received specific antibiotic therapy. The infections occurred sporadically over a period of nine months. Pseudomonas stutzeri was subsequently isolated from the dialysate that circulates within the hemodialysis machine. The ultimate source was the deionized water that is combined with the liquid concentrate to form the dialysate. Pseudomonas stutzeri could be localized to the top cannister of the dialysis machine but was also isolated throughout the machine, including the bottom reservoir and the recirculating pump. The emphasis on handwashing, strict compliance with disinfection procedures, and elimination of prolonged sitting times for the filled machine after disinfection resulted in no further cases of P stutzeri infection.

(Arch Intern Med 1983;143:1909-1912)