November 1983

Pulmonary Cryptococcosis and Cushing's Syndrome

Author Affiliations

From the Department of Medicine, State University of New York Downstate Medical Center, Brooklyn.

Arch Intern Med. 1983;143(11):2179-2180. doi:10.1001/archinte.1983.00350110169033

• Pulmonary cryptococcosis occurred in two patients with Cushing's syndrome, both of whom were successfully treated with amphotericin B and flucytosine. Excessive endogenous production of corticosteroids may have predisposed these patients to the development of opportunistic infection. Persons with Cushing's syndrome and a pulmonary infiltrate should be examined for infection with Cryptococcus neoformans In addition to an examination for ectopic adrenocorticotropic hormone production.

(Arch Intern Med 1983;143:2179-2180)