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November 1983

Focal Cerebral Ischemia and Mitral Valve Prolapse in Monozygotic Twins

Author Affiliations

From the Departments of Medicine (Drs Fisher and Budnitz) and Neurology (Dr Fisher), University of Massachusetts Medical Center, Worcester. Dr Fisher is now with Worcester (Mass) Memorial Hospital.

Arch Intern Med. 1983;143(11):2180-2181. doi:10.1001/archinte.1983.00350110170034

† Mitral valve prolapse (MVP) is a common frequently inherited cardiac valvular disorder. Ischemic cerebrovascular disease (ICVD) is an apparent complication of MVP. We report the concordance of MVP and ICVD in a pair of monozygotic twins. This occurrence reinforces the concepts that MVP is highly concordant in monozygotic twins and that it can be the cause of familial ICVD.

(Arch Intern Med 1983;143:2180-2181)