November 1983

Symptomatic Hypotension Following the Clonidine Suppression Test for Pheochromocytoma

Author Affiliations

From the Hypertension Unit, Brigham and Women's Hospital, and the Department of Medicine, Harvard Medical School, Boston.

Arch Intern Med. 1983;143(11):2195-2196. doi:10.1001/archinte.1983.00350110185039

• A 42-year-old man with generalized atherosclerosis underwent surgery of the left carotid artery with eventual placement of a Dacron graft bypassing the left carotid sinus. Subsequently, symptoms suggestive of pheochromocytoma developed, and 24-hour urine catecholamine levels were elevated. Clonidine testing resulted in suppression of plasma norepinephrine levels but was complicated by severe hypotension and a transient ischemic attack. Baroreceptor dysfunction may have been involved. Caution is advised and recommendations are offered for future usage of the clonidine suppression test.

(Arch Intern Med 1983;143:2195-2196)