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—Dr Courdi is correct in his definition of specificity. However, it is still true that the prediction of resistance by the in vitro assay is accurate 95% to 99% of the time, and the accuracy of a prediction of drug sensitivity is in the 60% to 65% range. On this basis, it is still true that the assay is better at identifying drugs to which a tumor is resistant.
Johnson PA. Assay Specificities-Reply. Arch Intern Med. 1983;143(12):2343. doi:10.1001/archinte.1983.00350120145046