January 1984

Clinical Use of Captopril in Takayasu's Disease

Author Affiliations

From the Department of Medicine D and the Hypertension Unit (Drs Grossman, Nussinovitch, Knecht, and Rosenthal), and the Departments of Roentgenology (Dr Morag) and Pediatrics (Dr Boichis), the Chaim Sheba Medical Center and Tel-Aviv University Medical School, Tel-Hashomer, Israel.

Arch Intern Med. 1984;144(1):95-96. doi:10.1001/archinte.1984.00350130107020

• Three patients with Takayasu's disease (TD), initially observed with hypertension and/or congestive heart failure, were treated with captopril, an orally active inhibitor of converting enzyme. As arteritis in this disease is diffuse and extensive, surgical correction of renovascular hypertension is often delayed or impossible. Our experience enables us to recommend captopril for conservative treatment in TD.

(Arch Intern Med 1984;144:95-96)