January 1984

Tumor Seeding Associated With Bone Marrow Aspiration and Biopsy

Author Affiliations

From the Medical Oncology Section, Veterans Administration Medical Center, Washington, DC.

Arch Intern Med. 1984;144(1):177. doi:10.1001/archinte.1984.00350130207038

• A 53-year-old man with small-cell lung carcinoma underwent bone marrow aspirations and biopsies for tumor staging and harvest for autologous bone marrow infusion. Fourteen months after bone marrow aspiration and biopsy, a subcutaneous lesion grew over the posterior iliac crest, and a biopsy specimen disclosed small-cell carcinoma. To our knowledge, this is the first case report of tumor seeding associated with bone marrow aspirate and biopsy.

(Arch Intern Med 1984;144:177)