edited by Benjamin Rothfeld, 458 pp, $50, Philadelphia, JB Lippincott Co, 1983.
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The editor states that the book is addressed to internists, clinical pathologists, and nuclear medicine specialists, with the goal of disseminating information on immunoassay techniques of value in clinical medicine. However, the book is more appropriate as a reference volume for radioassayists than as a source of readily comprehensible material for physicians without experience or a fairly sophisticated background in radioassay.
The first section focuses on fundamentals, with chapters on radioactivity counting, equipment, and performance parameters (an overview); statistics (a complex, abstruse chapter); radioimmunoassay method selection (a practical chapter for those embarking on a career in radioassay); principles of radioassay, including reaction kinetics (highly mathematic); and enzyme and fluorescent immunoassay (very technical). Basically, the section is too theoretic, mathematic, and recondite to interest the neophyte, but is worthwhile for the advanced student. It might have been more appropriately placed at the end of the book. A simpler, more straightforward explanation
Nusynowitz ML. Nuclear Medicine In Vitro. Arch Intern Med. 1984;144(3):457-458. doi:10.1001/archinte.1984.00350150041008