• It is well documented that patients with preexisting renal dysfunction are at increased risk of having nitrofurantoin-induced peripheral neuropathy develop. A diabetic patient whose condition was controlled by diet alone had peripheral neuropathy develop four days after starting nitrofurantoin therapy for the treatment of a urinary tract infection.
(Arch Intern Med 1984;144:821)
White WT, Harrison L, Dumas J. Nitrofurantoin Unmasking Peripheral Neuropathy in a Type 2 Diabetic Patient. Arch Intern Med. 1984;144(4):821. doi:10.1001/archinte.1984.00350160187030