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Article
June 1984

Hairy-Cell Leukemia With the Appearance of Mixed Cryoglobulinemia and Vasculitis

Author Affiliations

From the Department of Medicine, Veterans Administration Medical Center, and the Department of Internal Medicine, University of Mississippi Medical Center, Jackson.

Arch Intern Med. 1984;144(6):1300-1302. doi:10.1001/archinte.1984.00350180248038
Abstract

• Hairy-cell leukemia has been associated with a number of disorders of the immune system. At least 13 cases of vasculitis and hairy-cell leukemia have been reported. However, the occurrence of cryoglobulinemia and hairy-cell leukemia is rare. We report a case of a patient with the unusual combination of hairy-cell leukemia, vasculitis, and cryoglobulinemia. This case illustrates that hairy-cell leukemia should now be included in the differential diagnosis of patients with the appearance of vasculitis and cryoglobulinemia. The association presents a therapeutic challenge and emphasizes the need for individualized treatment in such patients.

(Arch Intern Med 1984;144:1300-1302)

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