• Hairy-cell leukemia has been associated with a number of disorders of the immune system. At least 13 cases of vasculitis and hairy-cell leukemia have been reported. However, the occurrence of cryoglobulinemia and hairy-cell leukemia is rare. We report a case of a patient with the unusual combination of hairy-cell leukemia, vasculitis, and cryoglobulinemia. This case illustrates that hairy-cell leukemia should now be included in the differential diagnosis of patients with the appearance of vasculitis and cryoglobulinemia. The association presents a therapeutic challenge and emphasizes the need for individualized treatment in such patients.
(Arch Intern Med 1984;144:1300-1302)
Raju SF, Chapman SW, Dreiling, B, Tavassoli M. Hairy-Cell Leukemia With the Appearance of Mixed Cryoglobulinemia and Vasculitis. Arch Intern Med. 1984;144(6):1300–1302. doi:10.1001/archinte.1984.00350180248038