• Obstructive airways diseases constitute 75% of all chronic respiratory diseases. This article briefly reviews the physiologic basis for flow limitation in large and small airways. Application of the physiologic principles described can lead to a better understanding of the normal mechanics of breathing and the various alterations resulting from diseases that limit airflow.
(Arch Intern Med 1984;144:1457-1460)
Robinson DR, Chaudhary BA, Speir WA. Expiratory Flow Limitation in Large and Small Airways. Arch Intern Med. 1984;144(7):1457–1460. doi:10.1001/archinte.1984.00350190153025