August 1984

Transmission of Hepatitis A by Transfusion of Blood Products

Author Affiliations

From the Division of Infectious Diseases, Departments of Medicine (Dr Sherertz) and Pediatrics (Dr Reuman), University of Florida School of Medicine, and the Department of Infection Control and Epidemiology, Shands Hospital (Dr Sherertz and Ms Russell), Gainesville, Fla.

Arch Intern Med. 1984;144(8):1579-1580. doi:10.1001/archinte.1984.00350200071011

• The transmission of hepatitis A by blood products has been thought to occur rarely or not at all. By measuring IgM antibody to hepatitis A virus, we diagnosed a case of hepatitis A transmitted by the transfusion of a unit of fresh frozen plasma. Since the commercial availability of methods for measuring IgM antibody to hepatitis A, four other well-defined cases of hepatitis A transmitted by blood products have been reported in the literature. We detail our case and the natural history and importance of this clinical entity.

(Arch Intern Med 1984;144:1579-1580)