September 1984

Disseminated Mycobacterial Disease Caused by Mycobacterium szulgai

Author Affiliations

From the Departments of Internal Medicine (Drs Gur, Naparstek, and Eliakim), Orthopedics (Dr Porat), and Clinical Microbiology (Dr Haas), Hadassah University Hospital, Jerusalem.

Arch Intern Med. 1984;144(9):1861-1863. doi:10.1001/archinte.1984.00350210191032

• Disseminated mycobacterial disease due to Mycobacterium szulgai occurred in a previously healthy young man. The clinical picture included fever, mediastinal and generalized lymphadenopathy, hemoptysis, and skin lesions but was dominated by progressive multifocal osteomyelitis. Immunological studies revealed a decrease in T-lymphocyte reaction to mitogens, but this was tested late in the course of the disease and may have been secondary. In spite of repeated surgical drainage and treatment with multiple antituberculous drugs for a period of two years, new lesions continue to appear mainly in the bones. Mycobacterium szulgai was isolated from 28 bone specimens, as well as from skin lesions and sputum. To the best of our knowledge, this is the first report of disseminated disease due to this organism.

(Arch Intern Med 1984;144:1861-1863)