October 1984

[ill]rimary Hyperparathyroidism Complicated by Multiple Myeloma

Author Affiliations

From the Division of Metabolism, Department of Medicine, Washington [ill]niversity School of Medicine, St Louis (Dr Hoelzer), and the Division of [ill]docrinology, Department of Internal Medicine, St Louis University [ill]hool of Medicine (Dr Silverberg).

Arch Intern Med. 1984;144(10):2069-2071. doi:10.1001/archinte.1984.04400010196034

• A patient with primary hyperparathyroidism and multiple [ill]yeloma did not have roentgenographic evidence of either [ill]sease, yet there was biochemical evidence for both dis[ill]ses. Hyperparathyroidism was diagnosed by hypercalcemia [ill]nd increased parathyroid hormone values. Multiple myeloma [ill]as diagnosed by serum γ-globulin component of 2.74 g/dL [ill]ith a monoclonal spike and bone marrow plasmacytosis of [ill]%. The serum IgA level was 2.22 g/dL and the IgG and IgM [ill]vels were normal. Serum and urine immunoelectrophoresis [ill]howed abnormal IgA and lambda arcs. Computed tomogra[ill]hy of the neck localized a parathyroid adenoma that was [ill]und and removed at surgery.

(Arch Intern Med 1984;144:2069-2071)