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November 1984

Failure of Colchicine in the Treatment of Mollaret's Meningitis

Author Affiliations

From the Department of Medicine, University of Alabama in Birmingham.

Arch Intern Med. 1984;144(11):2265-2266. doi:10.1001/archinte.1984.04400020194033

• A 32-year-old man was hospitalized 23 times in 11 years because of attacks of Mollaret's meningitis. Colchicine (0.6 mg twice daily) was administered for 15 months but failed to decrease the severity or the frequency of attacks. The prophylactic efficacy of drugs in Mollaret's meningitis is difficult to assess because episodes are unpredictable and remissions occur spontaneously. There remains no established therapy for Mollaret's meningitis.

(Arch Intern Med 1984;144:2265-2266)