February 1985

Preleukemia and Urticaria Pigmentosa Followed by Acute Myelomonoblastic Leukemia

Author Affiliations

From the Department of Internal Medicine, University of Cincinnati College of Medicine.

Arch Intern Med. 1985;145(2):349-352. doi:10.1001/archinte.1985.00360020193033

• A preleukemic syndrome, mast cell hyperplasia in the bone marrow, and urticaria pigmentosa simultaneously developed in a 76-year-old woman. A year later, the patient died of acute myelomonoblastic leukemia. These associations provide evidence favoring the origin of the tissue mast cell from a bone marrow stem cell.

(Arch Intern Med 1985;145:349-352)