• A 61-year-old man with end-stage renal disease developed severe hyperventilation following nortriptyline hydrochloride usage for depression. He required mechanical ventilation and paralysis to correct severe respiratory alkalosis. To our knowledge, nortriptyline usage has not been previously associated with hyperventilation.
(Arch Intern Med 1985;145:746-747)
Sunderrajan S, Brooks CS, Sunderrajan EV. Nortriptyline-Induced Severe Hyperventilation. Arch Intern Med. 1985;145(4):746-747. doi:10.1001/archinte.1985.00360040184041