May 1985

Treatment of Central Nervous System Fungal Infection With Ketoconazole

Author Affiliations

From the Department of Internal Medicine, University of Kansas School of Medicine—Wichita.

Arch Intern Med. 1985;145(5):879-880. doi:10.1001/archinte.1985.00360050135023

• Two patients with fungal infection of the central nervous system (coccidioidal meningitis and cerebral histoplasmomas) were treated with ketoconazole for 30 months. Both responded to dosages substantially less than those described previously for similar infections. Neither patient experienced any significant adverse effects from the prolonged therapy.

(Arch Intern Med 1985;145:879-880)