May 1985

Hyperthyroidism and Addison's Disease in a Patient With Myotonic Dystrophy

Author Affiliations

From the Department of Internal Medicine, Hospital of Avellino (Drs Pagliara, Spagnuolo, Ambrosone, and Barbato), and the University of Naples (Drs Tesauro and Rambaldi), Italy.

Arch Intern Med. 1985;145(5):919-920. doi:10.1001/archinte.1985.00360050189033

• A 53-year-old man had myotonic dystrophy, hyperthyroidism, and Addison's disease, an association not previously reported, to our knowledge. In the literature, at least five cases of hyperthyroidism associated with myotonic dystrophy have been described, but none also had Addison's disease. The presence of thyroid antimicrosomal antibodies and antiadrenal antibodies suggests that the two endocrine disorders may be autoimmune. In our case, the treatment of the two endocrinopathies caused a reduction of myotonic symptoms.

(Arch Intern Med 1985;145:919-920)