May 1985

Ultrasonography in the Diagnosis and Follow-up of Hepatic Sinusoidal Dilatation

Author Affiliations

From the Departments of Internal Medicine C (Drs Weinberger, Garty, and Rosenfeld) and Radiology (Drs Cohen and Russo), Beilinson Medical Center and Sackler School of Medicine, Tel Aviv University, Petah Tiqva, Israel.

Arch Intern Med. 1985;145(5):927-929. doi:10.1001/archinte.1985.00360050197037

• Hepatic sinusoidal dilatation is a rare complication of oral contraceptive use. A 29-year-old woman who had been taking oral contraceptive pills for eight years was found to have persistently elevated erythrocyte sedimentation rates and alkaline phosphatase levels, hepatomegaly, diffuse hepatic sinusoidal dilatation, and a large nonhomogeneous hyperechogenic lesion in the right hepatic lobe. The abdominal ultrasonogram, liver size, erythrocyte sedimentation rates, and alkaline phosphatase levels reverted to normal within 24 months after discontinuing oral contraceptives. This case should encourage the use of abdominal ultrasonography in detection and follow-up of hepatic sinusoidal dilatation.

(Arch Intern Med 1985;145:927-929)