• In a patient undergoing radiation therapy for recurrent, metastatic breast cancer, a mixture of propoxyphene and acetaminophen (Darvocet) was given for intercurrent viral infection. Discontinuation of therapy with this medication coincided with appearance of pneumonitis, reminiscent of the steroid withdrawal—related radiation pneumonitis.
(Arch Intern Med 1985;145:1509-1510)
Halpern J, Baerwald H, Johnson R, Takita H, Ambrus JL. Propoxyphene and Acetaminophen Mixture (Darvocet)—Related Radiation-Induced Pneumonitis. Arch Intern Med. 1985;145(8):1509-1510. doi:10.1001/archinte.1985.00360080191028