• Plasma and ultrafiltrate drug concentrations were determined for 17 drugs in ten patients receiving continuous arteriovenous hemofiltration. Ultrafiltrate concentrations were not always predictable because of multiple factors, which may include altered drug-protein binding in these very ill patients.
(Arch Intern Med 1985;145:1651-1652)
Golper TA, Pulliam J, Bennett WM. Removal of Therapeutic Drugs by Continuous Arteriovenous Hemofiltration. Arch Intern Med. 1985;145(9):1651–1652. doi:10.1001/archinte.1985.00360090119018