January 1986

Salmonella Bacteremia as Manifestation of Acquired Immunodeficiency Syndrome

Author Affiliations

From the Divisions of General Internal Medicine (Drs Fischl and Pitchenik) and Infectious Diseases (Drs Dickinson and Sinave), Department of Medicine (Drs Fischl, Dickinson, Sinave, and Pitchenik), and the Department of Pathology (Dr Cleary), University of Miami School of Medicine.

Arch Intern Med. 1986;146(1):113-115. doi:10.1001/archinte.1986.00360130139019

Multiple opportunistic infections are characteristic of the acquired immunodeficiency syndrome (AIDS). Although bacterial pathogens have presented few problems, we have noted an emerging problem with salmonellal infection among patients with AIDS. A review of all stool and blood cultures from adults between January 1982 and July 1984 showed that 80 stool cultures were positive for Salmonella species; serogroup B was the most common isolated. Eight (10%) were isolated from patients with AIDS. Nineteen blood cultures were positive for Salmonella species. Six (32%) were isolated from patients with AIDS: three were positive for Salmonella serogroup B; two yielded Salmonella choleraesuis; and one yielded Salmonella serogroup D. In three (50%), Salmonella bacteremia was a presenting manifestation of AIDS. Bacteremias were recurrent in five patients. Thus, it appears that AIDS not only predisposes patients to serious salmonellal infections but also compromises their ability to eradicate these bacteria.

(Arch Intern Med 1986;146:113-115)