January 1986

Successful Treatment of Meningeal Myeloma With Combination of Radiation Therapy, Chemotherapy, and Intrathecal Therapy

Author Affiliations

From the Departments of Medical Oncology (Dr Gomez) and Radiation Therapy (Dr Krishnamsetty), Roswell Park Memorial Institute, Buffalo.

Arch Intern Med. 1986;146(1):194-196. doi:10.1001/archinte.1986.00360130236033

Meningeal involvement is a rare complication of multiple myeloma. None of the previously described patients presenting this syndrome had responded to treatment. We describe a 64-year-old man with meningeal myelomatosis. A favorable response to treatment was produced by radiation therapy administered to the head and by intrathecal and systemic chemotherapy including high-dose corticosteroids.

(Arch Intern Med 1986;146:194-196)