February 1986

When to Intervene in Chronic Aortic Regurgitation

Author Affiliations

From the Department of Medicine (Cardiology), Tufts University School of Medicine (Dr Gaasch), and the Boston Veterans Administration Medical Center (Drs Gaasch and Hoshino), Boston. Dr Hoshino is a research fellow in cardiology of the American Heart Association, Massachusetts Affiliate, Inc.

Arch Intern Med. 1986;146(2):349-352. doi:10.1001/archinte.1986.00360140179026

• Symptomatic patients with chronic aortic regurgitation should undergo aortic valve replacement. Asymptomatic patients with normal left ventricular function are not surgical candidates, but aortic valve replacement should be performed in most patients with left ventricular dysfunction, even if symptoms are not yet present. The short-term administration of vasodilators is generally beneficial, but there is only meager evidence that the hemodynamic benefits are maintained; for this reason, the wide application of these agents should be postponed until well-designed clinical trials document a longterm benefit.

(Arch Intern Med 1986;146:349-352)