March 1986

Purpura Fulminans in Pneumococcal Sepsis

Author Affiliations

From the Departments of Hematology (Drs Hautekeete, Berneman, and Peetermans), Clinical Immunology (Dr Stevens and Mr Bridts), and Pathology (Dr Buyssens), University of Antwerp (Belgium); and the Department of Internal Medicine, Deaconess Hospital "Bronovo," The Hague (Dr Bieger).

Arch Intern Med. 1986;146(3):497-499. doi:10.1001/archinte.1986.00360150107012

• Two cases of pneumococcal sepsis in splenectomized patients were complicated by purpura fulminans. In addition, acute renal failure developed in both patients, and myolysis in one. Immunological findings in the patient with myolysis suggest a possible role of pneumococcal antigen-containing circulating immune complexes in the pathogenesis of these complications.

(Arch Intern Med 1986;146:497-499)