• Three patients had severe amphotericin B—induced rigors refractory to conventional prophylactic measures. Rigors improved or disappeared when dantrolene sodium was given prophylactically or during an episode. These observations suggest that dantrolene is useful as an alternative or adjuvant agent for severe rigors associated with amphotericin B infusion.
(Arch Intern Med 1986;146:1587-1588)
Gross MH, Fulkerson WJ, Moore JO. Prevention of Amphotericin B—Induced Rigors by Dantrolene. Arch Intern Med. 1986;146(8):1587-1588. doi:10.1001/archinte.1986.00360200157025