To the Editor.
—The article on quinidine-induced hepatitis by Knobler et al1 is interesting and important. Curiously, no mention is made of the reason why quinidine was given to 1500 patients in a ten-year period at their hospital. Hopefully, the recovery that occurred after cessation of the drug will not encourage its use. Indeed, although quinidine is widely used (and has been for a long time) in the prevention and treatment of various arrhythmias, it use remains moot, and adverse effects continue to be emphasized.2 Yet, it is certain that in most, if not all, instances the use of quinidine can be avoided.
Zatuchni J. Quinidine-Induced Hepatitis. Arch Intern Med. 1986;146(10):2077. doi:10.1001/archinte.1986.00360220259044