• Seventy-three consecutive diabetic adults with symptomatic peripheral neuropathy were evaluated for the presence of cardiovascular autonomic neuropathy and electrocardiographic evidence of myocardial infarction (MI). Twenty-five (34.2%) patients demonstrated cardiovascular autonomic neuropathy, and ten (13.7%) patients had electrocardiographic evidence of MI. Of the ten MI identified, seven were asymptomatic (silent) by history. The incidence of silent MI was significantly higher (P<.04) in patients with cardiovascular autonomic neuropathy. It is postulated that sudden death in diabetic patients with cardiovascular autonomic neuropathy may be due to silent MI.
(Arch Intern Med 1986;146:2229-2230)
Niakan E, Harati Y, Rolak LA, Comstock JP, Rokey R. Silent Myocardial Infarction and Diabetic Cardiovascular Autonomic Neuropathy. Arch Intern Med. 1986;146(11):2229-2230. doi:10.1001/archinte.1986.00360230169023